Kyriakos P Papadopoulos Selected Research

((S)- 2- (5- (1,2- dihydro- 3- methyl- 1- oxobenzo(f)- quinazoline- 9- yl)methyl)amino- 1- oxo- 2- isoindolynyl)- glutaric acid

12/2008

Phase I, pharmacokinetic and biological correlative study of OSI-7904L, a novel liposomal thymidylate synthase inhibitor, and cisplatin in patients with solid tumors.

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Kyriakos P Papadopoulos Research Topics

Disease

64	Neoplasms (Cancer) 10/2022 - 12/2002
15	Fatigue 01/2022 - 06/2012
10	Exanthema (Rash) 10/2020 - 05/2009
8	Nausea 01/2022 - 06/2013
7	Multiple Myeloma 01/2019 - 01/2015
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2022 - 01/2016
5	Renal Cell Carcinoma (Grawitz Tumor) 10/2021 - 10/2016
4	Colorectal Neoplasms (Colorectal Cancer) 10/2022 - 01/2016
4	Vomiting 02/2017 - 06/2013
4	Neutropenia 02/2017 - 06/2013
3	Diarrhea 01/2022 - 06/2013
3	Hypoxia (Hypoxemia) 10/2021 - 11/2008
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021 - 01/2018
3	Thrombocytopenia (Thrombopenia) 11/2019 - 06/2013
3	Glioblastoma (Glioblastoma Multiforme) 01/2019 - 01/2016
3	Breast Neoplasms (Breast Cancer) 10/2018 - 01/2016
3	Febrile Neutropenia 08/2018 - 06/2013
2	Melanoma (Melanoma, Malignant) 01/2021 - 01/2016
2	Body Weight (Weight, Body) 01/2021 - 01/2018
2	Adenocarcinoma 01/2021 - 11/2020
2	Edema (Dropsy) 10/2020 - 10/2017
2	Dermatitis 01/2020 - 01/2018
2	Lymphoma (Lymphomas) 01/2020 - 06/2015
2	Anemia 01/2020 - 06/2012
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2019 - 01/2016
2	Hypokalemia 01/2018 - 01/2015
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2018 - 06/2012
2	Stomatitis 02/2017 - 02/2015
2	Mucositis 02/2017 - 04/2012
2	Hypertension (High Blood Pressure) 09/2016 - 05/2009
2	Hepatocellular Carcinoma (Hepatoma) 03/2016 - 10/2004
2	Pruritus (Itching) 03/2016 - 08/2014
2	Prostatic Neoplasms (Prostate Cancer) 11/2014 - 06/2009
2	Proteinuria 05/2014 - 05/2009
2	Alopecia (Baldness) 05/2014 - 06/2013
1	Squamous Cell Carcinoma of Head and Neck 01/2021

Drug/Important Bio-Agent (IBA)

7	Pharmaceutical PreparationsIBA 01/2019 - 06/2013
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 11/2014
6	Immune Checkpoint InhibitorsIBA 03/2021 - 01/2018
6	Monoclonal AntibodiesIBA 01/2021 - 05/2014
6	cemiplimabIBA 01/2021 - 01/2018
5	pembrolizumabIBA 01/2021 - 10/2015
5	ErbB Receptors (EGF Receptor)IBA 01/2019 - 12/2017
4	Erlotinib Hydrochloride (CP 358,774)FDA Link 03/2022 - 05/2009
4	pegilodecakinIBA 01/2021 - 11/2018
3	Docetaxel (Taxotere)FDA Link 03/2022 - 01/2014
3	Aspartate Aminotransferases (Aspartate Transaminase)IBA 10/2020 - 01/2015
3	Lipase (Acid Lipase)FDA Link 01/2020 - 03/2014
3	Midazolam (Versed)FDA LinkGeneric 01/2019 - 11/2014
3	Proteasome InhibitorsIBA 01/2019 - 10/2013
3	depatuxizumab mafodotinIBA 01/2019 - 12/2017
3	Phosphotransferases (Kinase)IBA 08/2018 - 10/2007
3	carfilzomibIBA 01/2017 - 10/2013
3	Hormones (Hormone)IBA 03/2016 - 06/2009
3	Phosphatidylinositols (Phosphatidylinositol)IBA 06/2015 - 04/2012
3	MK 2206IBA 02/2015 - 01/2014
3	Cisplatin (Platino)FDA LinkGeneric 12/2008 - 10/2003
2	adagrasibIBA 10/2022 - 01/2020
2	glesatinibIBA 03/2022 - 01/2022
2	NivolumabIBA 01/2022 - 11/2019
2	belzutifanIBA 10/2021 - 01/2021
2	Immunoglobulin G (IgG)IBA 01/2021 - 09/2017
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 01/2020
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2021 - 06/2003
2	Tyrosine Kinase InhibitorsIBA 01/2021 - 10/2007
2	Macrophage Colony-Stimulating FactorIBA 10/2020 - 10/2017
2	ONX 0912IBA 01/2019 - 04/2016
2	Cytochrome P-450 CYP3AIBA 01/2019 - 01/2018
2	Immunoconjugates (Immunoconjugate)IBA 12/2018 - 01/2018
2	Interleukin-10 (Interleukin 10)IBA 11/2018 - 10/2016
2	trametinibIBA 09/2016 - 01/2015
2	SurvivinIBA 01/2016 - 06/2012
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2016 - 10/2013
2	sepantroniumIBA 01/2016 - 06/2012
2	TOR Serine-Threonine KinasesIBA 06/2015 - 10/2012
2	XL765IBA 06/2015 - 05/2014
2	Dexamethasone (Maxidex)FDA LinkGeneric 03/2015 - 08/2014
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 02/2015 - 01/2015
2	ridaforolimusIBA 11/2014 - 10/2012
2	ProdrugsIBA 11/2014 - 11/2008
2	vesencumabIBA 08/2014 - 05/2014
2	Bevacizumab (Avastin)FDA Link 05/2014 - 05/2009
2	Paclitaxel (Taxol)FDA LinkGeneric 05/2014 - 01/2014
2	Transaminases (Aminotransferases)IBA 06/2013 - 04/2012
2	Biological ProductsIBA 12/2010 - 12/2008
2	Peptides (Polypeptides)IBA 06/2003 - 12/2002
1	Inducible T-Cell Co-Stimulator ProteinIBA 01/2022
1	envafolimabIBA 01/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021
1	Transcription Factors (Transcription Factor)IBA 01/2021
1	Leucovorin (Folinic Acid)FDA Link 01/2021
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2021
1	MK-4166IBA 01/2021
1	GlucocorticoidsIBA 01/2021

Therapy/Procedure

14	Therapeutics 03/2021 - 10/2007
4	Radiotherapy 01/2021 - 03/2016
4	Drug Therapy (Chemotherapy) 03/2016 - 10/2003
2	Immunotherapy 03/2021 - 06/2003
1	Subcutaneous Injections 01/2021
1	Intravenous Administration 01/2021